Enseleni Nature reserve consists of coastal grasslands and forest and the Nseleni river provides a freshwater habitat. For birding enthusiasts the reserve boasts several unusual or rare species, namely African finfoot, purple crested lourie, Pels fishing owl, white-eared barbet and three species of elusive nightjars, Mozambique, fiery necked and European. 

Game species occurring in the reserve include giraffe, wildebeest, zebra, impala, reedbuck, waterbuck, bushbuck, bushpig, red, blue and grey duiker, hippopotamus, crocodile, large-spotted genet and the shy bushbaby.

No accommodation, camping or caravanning is available in the reserve. Only picnic sites are available. No bookings are necessary for picnicking. There are two trails in the reserve, which offer fantastic scenery and the opportunity to experience different parts of the reserve and to spot a variety of birds and animals. The Nkonkoni trail is 7 km and the Mvubu trail is 2 km in length.

Please note that from the 1st of August 2008 an entry fee to Enseleni Nature Reserve will be charged. This will be R10 per adult and R5 per child, 12 years old and under.